In my usual order, just in time for the evening snack, I checked my email to see whats new. Mr. Zaya had sent the official White pepper from El Septimo and I couldn’t stop reading. Things I’ve never read or known before, facts I don’t think many others know. The information i got, read it here below.

I. INTRODUCTION — WHY THIS REPORT EXISTS
For over a century, the world has made the critical mistake of grouping premium natural cigars together with chemical cigarettes, assuming they are biologically identical because both contain tobacco.
That is false — scientifically, chemically, and medically. Cigarettes are a synthetic nicotine delivery system, engineered with over 7,000 added chemicals, ammonia accelerants, and designed specifically for deep lung inhalation and instant brain spike addiction.
Premium cigars — especially at the El Septimo standard — are 100% natural agricultural products.
No chemicals. No inhalation. Slow biological absorption through the oral mucosa — the same delivery pathway as sublingual pharmaceutical therapy.
This white paper exists to correct the false narrative that has gone unchallenged for decades. Cigars are not cigarettes. And natural nicotine is not the enemy. Now let’s find out the truth about benefits of natural nicotine found in premium cigars.
II. WHAT NICOTINE & ALKALOIDS REALLY ARE
Nicotine is not a synthetic drug created by the tobacco industry. It is a natural botanical alkaloid — found in the same pyridine alkaloid family as:
Tomatoes
Eggplants
Green peppers
Potatoes
Cauliflower
These are consumed safely by humans every day. Even more importantly:
✅ Nicotine Is an alkaloid.
✅ Cigars contain multiple natural alkaloids — not just nicotine (nornicotine, anatabine, myosmine, anabasine).
✅ These alkaloids exist naturally in the leaf — not “added” — not “engineered.”
The human body contains dedicated receptors such as α7-nicotinic acetylcholine receptors, designed by biology to interact with natural alkaloids — just like plant polyphenols, caffeine, theobromine, etc. Natural nicotine is not the problem. Chemical manipulation and inhalation are the problem.

El Septimo Scientist have discovered that the health benefits of Pyridine Alkaloid in human body is significant and directly benefits the following:


Conclusion:
Cigars — especially El Septimo — are not a smoking product in the sense cigarettes are. They are a botanical alkaloid experience, absorbed orally, never entering the lungs, never chemically manipulated.
IV. HEALTH BENEFITS OF NATURAL NICOTINE & PYRIDINE ALKALOIDS
This section now includes the full alkaloid research you requested integrated professionally. Modern research has confirmed that pyridine alkaloids — when delivered naturally and not inhaled — may support:
✅ Anti-Inflammatory & Antioxidant
Suppresses TNF-α, IL-6, NF-KB inflammation markers
Supports arthritis, inflammatory bowel conditions, and immune balance
Neutralizes free radicals — improves nutrient bioavailability
✅ Anticancer Potential
Natural nicotine under non-inhaled conditions can inhibit tumor proliferation
Triggers apoptosis (self-destruction) in breast, colon & lung cancer cell lines
Industrial cigarette data does NOT apply — due to chemical combustion
✅ Antidiabetic & Anti-Obesity
Slows glucose absorption
Improves insulin sensitivity
Reduces fat accumulation in liver & muscle tissues
✅ Neuroprotective / Cognitive
Modulates acetylcholine, dopamine, serotonin, norepinephrine
Protects brain function — studied in Alzheimer’s & Parkinson’s
May reduce seizure activity
✅ Antimicrobial & Antifungal
Attacks bacteria & fungi, including drug-resistant strains
Supports oral microbiome balance
✅ Natural Analgesic (Pain Relief)
Reduces pain signaling — mild opioid-like effect WITHOUT addiction mechanics
Historically used for rheumatism & joint inflammation
✅ Digestive & Cardiovascular Support
Strengthens stomach lining (gastroprotective)
Supports healthy cholesterol processing
Natural expectorant & airway support




Would you like more about Zaya Younan and and El Septimo? Read our interview: The story of Zaya Younan and El Septimo. A living proof that anything is possible


Subscribe to our newsletter and find out about all new posts
Check out our latest posts
- How VDG Cigars Reviews a Cigar — The Full Methodology Explained
There are thousands of cigar reviews published every year. Most of them follow the same formula. Someone lights up, jots… Read more: How VDG Cigars Reviews a Cigar — The Full Methodology Explained - El Septimo Paris review
Construction Lets start our review of the El Septimo Paris with the construction. This cigar was as all the other… Read more: El Septimo Paris review - The Robusto: Why It Became the World’s Most Popular Cigar Size
Walk into any cigar shop in the world and the robusto will be the size filling most of the humidor.… Read more: The Robusto: Why It Became the World’s Most Popular Cigar Size - Matilde Serena maduro robusto review
Construction I was a little concerned before i lit up the Matilde Serena maduro, when i inspected the cigar i… Read more: Matilde Serena maduro robusto review - Small Batch vs Large Production Cigars: Does Scale Affect Quality?
By Peter | VDG Cigars | Certified Cigar Sommelier I’ll tell you where I stand: I love small batch cigars.… Read more: Small Batch vs Large Production Cigars: Does Scale Affect Quality? - How to Buy Cigars Online: The Complete Buyer’s Guide
Buying cigars online is becoming more and more popular — and anyone who has been paying attention to the premium… Read more: How to Buy Cigars Online: The Complete Buyer’s Guide - Chateau Diadem Conviction Petit Belicoso review
Construction I was a surprised by the construction of the Chateau Diadem Conviction Petit Belicoso when i opened the deliver… Read more: Chateau Diadem Conviction Petit Belicoso review - How to Develop Your Cigar Palate: The Complete Guide
Most cigar smokers taste far less than what is actually in their cigars. Not because their palate is defective, but… Read more: How to Develop Your Cigar Palate: The Complete Guide



